Characterization and Similarity Analysis of DNA Sequences Considering Codon Degeneracy

نویسندگان

  • Yong-Bin Zhao
  • Zhao-Hui Qi
  • Ai-Ping Yang
چکیده

We introduce a new 2D graphic representation of DNA sequences considering codon degeneracy. Derived from the graphic representation, a multi-component vector is proposed to characterize quantitatively DNA sequences. Then we use the graphic representation and the vector to perform the phylogenetic analysis on two datasets, the complete coding sequences of the  -globin genes of 11 species and the HA genes of 16 influenza A (H1N1) isolates. The experimental assessment demonstrates the efficiency of the proposed method.

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تاریخ انتشار 2015